Press Release

Press Release

News & Press – Press Release

Announcing the Release of New and Improved Revivogen Formula with Caffeine
Feb. 9, 2011
Los Angeles, CA, USA


In keeping with our commitment to provide the most powerful products for androgenic alopecia using scientifically proven natural ingredients, Advanced Skin and Hair, Inc. announces the release of its newest Scalp Therapy formula utilizing to increase effectiveness as well as other improvements to the look, feel and smell of Revivogen Scalp Therapy to enhance user experience.

New Ingredient CAFFEINE:
Recent studies have shown that not only Caffeine reverses the suppressive effects of Testosterone on the follicle but also is a very strong stimulator of the hair follicle growth. Caffeine along with Procyanidin Oligomers another proven growth stimulant available in Revivogen provide the most comprehensive, scientifically proven natural growth stimulation combination available in any natural product.

The new combination of powerful growth stimulants Caffeine and Procyanidin Oligomers in addition to the strongest natural 5AR and androgen receptor blockers, create the most comprehensive and powerful Revivogen formula to date which remains unsurpassed by other natural products in the market.

Other Enhancements:
In order to increase customer satisfaction and enhance user experience the new formula is now lighter in color to avoid staining of fair colored hair, has a new, more pleasant minty smell, fells less oily and absorbs faster. These changes were accomplished without any changes to the amount or quality of the beneficial ingredients used in Revivogen.
The new formula has been available and shipped to all customers and vendors since Oct. 2010 so if you have purchased Revivogen scalp therapy during the past few months you already have the new formula.

International Journal of Dermatology. (January 2007). 6 (1): 27–35.
“Effect of caffeine and testosterone on the proliferation of human hair follicles in vitro”.
Fischer TW, Hipler UC, Elsner P

Hair follicles from 14 biopsies, taken from the vertex areas from male AGA patients, were cultivated for 120–192 h in vitro with normal William’s E medium (control) or William’s E medium containing different concentrations of testosterone and/or caffeine. Hair shaft elongation was measured daily and at the end of cultivation, cryosections of follicles were stained with Ki-67 to evaluate the degree and localization of keratinocyte proliferation.


Significant growth suppression was found in hair follicles treated with 5 µg/ml testosterone. This was counteracted by caffeine in concentrations of 0.001% and 0.005%. Moreover, caffeine alone led to a significant stimulation of hair follicle growth. These results were confirmed immunohistochemically by Ki-67 staining.


Androgen-dependent growth inhibition of ex vivo hair follicles from patients suffering from AGA was present in the human hair organ culture model, a constellation which may serve for future studies to screen new substances against androgen-dependent hair loss. Caffeine was identified as a stimulator of human hair growth in vitro; a fact which may have important clinical impact in the management of AGA.